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Medical Disclaimer
This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making changes to your health regimen, especially if you have underlying health conditions.
Up to 70% of people with type 2 diabetes have fatty liver, and most have no idea it’s there.
In this episode of the Taking Control of Your Diabetes Podcast, Drs. Steve Edelman and Jeremy Pettus sit down with patient Manuel to hear how a slightly abnormal liver enzyme on a routine blood test led to a high-stage 3 MASH diagnosis (metabolic dysfunction-associated steatohepatitis, formerly known as NASH) — and how he turned it around.
Manuel walks through his full journey: the elevated enzyme levels his primary care doctor caught during an annual physical, the 100 pounds he gained during COVID, his work with hepatologist Dr. Julio Gutierrez at Scripps, his gastric bypass, and his year on Rezdiffra (resmetirom). His fibrosis has regressed, he’s gained 30 pounds of muscle, and he’s now a few months between specialist visits instead of facing a transplant conversation.
00:00 Introduction to Fatty Liver and MASH
01:38 Meet Manuel: A Patient’s Journey
02:45 What is Fibrosis? Dr. Gutierrez Explains
04:42 Manuel’s Diagnosis and Medical Background
07:32 Who to See First and Staging Fibrosis
08:37 COVID-19 Weight Gain and Stage 3 Diagnosis
13:22 Visualizing Liver Damage: Healthy to Cirrhosis
16:02 Understanding the FIB-4 Score
17:16 Treatment Options: Lifestyle, GLP-1s, and Rezdiffra
18:58 Gastric Bypass and Manuel’s Medication Experience
22:16 Health Improvements and Reversing Fibrosis
25:06 Cardio-Renal-Hepatic Syndrome Explained
27:24 The Importance of Early Diagnosis
If you live with type 2 diabetes, prediabetes, or carry extra weight around your middle, this is the episode to watch.
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#FattyLiver #MASH #NASH #Type2Diabetes #LiverHealth #Rezdiffra #DiabetesPodcast #TCOYD #GLP1 #LiverFibrosis
Sean Thompson, MS, MPH, RD, LDN
Registered Dietitian, Nourish
“Based preloads can be a practical tool for bariatric patients who struggle with portion control,” says Sean Thompson, a Northampton-based dietitian with a 4.99-star rating across 385+ reviews. “But I always tell clients: the foundation is still protein-first meals and mindful eating. Think of the gelatin trick as training wheels, not the whole bike. And if you have kidney concerns, check with your doctor — excessive gelatin can be protein overkill.”
Sean specializes in accessible, evidence-based nutrition for individuals with disabilities and those navigating post-surgical diets. She holds dual master's degrees from Tufts University and approaches care without a weight-centric lens.
